Definition of frameshift
frame´shift
a.
1.
(Genetics)
of
,
pertaining
to
,
or
causing
a
type
of
mutation
consisting
of
the
insertion
or
deletion
of
one
or
more
nucleotides
in
the
nucleic
acid
structure
of
a
gene
,
when
the
number
of
base
pairs
inserted
or
deleted
is
not
a
multiple
of
three
.
If
the
addition
or
deletion
occurs
in
multiples
of
three
,
the
unaffected
nucleotides
in
the
genome
remain
in
the
proper
order
("
frame
")
to
be
correctly
translated
into
protein
;
in
such
cases
of
insertions
or
deletions
not
causing
a
frame
shift
,
a
functional
though
altered
protein
may
be
produced
by
the
organism
.
Frameshift
mutations
cause
more
profound
changes
in
the
composition
of
the
protein
resulting
from
translation
of
the
mutated
gene
.
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Fraight
frail
frailly
frailness
frailty
Fraischeur
Fraise
Fraised
Fraken
Framable
Frambaesia
Frame
Frame building
Frame level
Frame of mind
Frame of reference
Frame saw
Frame-up
framed
Framer
Framework
Framing
Framing chisel
Frampel
Franc
franc-tireur
Franchise
Franchisement
Francic
Franciscan
Franciscan Brothers
Franciscan Nuns
Franciscan Tertiaries
Francolin
Francolite
Francophil
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Francophone
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